cGAS

Bacterial cGAS-like enzymes produce 2′,3′-cGAMP to activate an ion channel that restricts phage replication
Jul 26, 2023
Tak U, Walth P, ➤Whiteley AT | BioRxiv 2023
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Analysis of human cGAS activity and structure
May 2, 2019
Zhou W, ➤Whiteley AT, Kranzusch PJ. | Methods Enzymol. 2019
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Bacterial cGAS-like enzymes synthesize diverse nucleotide signals
Mar 1, 2019
➤Whiteley AT, Eaglesham JB, de Oliveira Mann CC, Morehouse BR, Lowey B, Nieminen EA, Danilchanka O, King DS, Lee ASY, Mekalanos JJ*, Kranzusch PJ* | Nature. 2019
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Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance
Jul 12, 2018
Zhou W*, ➤Whiteley AT*, de Oliveira Mann CC, Morehouse BR, Nowak RP, Fischer ES, Gray NS, Mekalanos JJ, Kranzusch PJ. | Cell. 2018
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